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Carbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells.

Cell Cycle. 2013;12:1791-801

Fiaschi T, Giannoni E, Taddei ML, Cirri P, Marini A, Pintus G, Nativi C, Richichi B, Scozzafava A, Carta F, Torre E, Supuran CT, Chiarugi P.

Regulation of the Na+/H+ Exchanger (NHE1) in Breast Cancer Metastasis

Cancer Res. 2013;73:1259-64.

Amith SR, Fliegel L.

Histone acetylation regulates intracellular pH

Mol Cell 2013;49:310-21

McBrian MA, Behbahan IS, Ferrari R, Su T, Huang TW, Li K, Hong CS, Christofk HR, Vogelauer M, Seligson DB, Kurdistani SK.

Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells.

PLoS One. 2012;7:e46571

De Saedeleer CJ, Copetti T, Porporato PE, Verrax J, Feron O, Sonveaux P.

Autophagy is a protective mechanism for human melanoma cells under acidic stress

J Biol Chem 2012; 287:30664-76

Marino ML, Pellegrini P, Di Lernia G, Djavaheri-Mergny M, Brnjic S, Zhang X, Hägg M, Linder S, Fais S, Codogno P, De Milito A

Novel molecular mechanisms of antitumor action of dichloroacetate against T cell lymphoma: Implication of altered glucose metabolism, pH homeostasis and cell survival regulation.

Chem Biol Interact. 2012;199:29-37

Kumar A, Kant S, Singh SM.

Modulation of microenvironment acidity reverses anergy in human and murine tumor-infiltrating T lymphocytes.

Cancer Res. 2012;72:2746-56

Calcinotto A, Filipazzi P, Grioni M, Iero M, De Milito A, Ricupito A, Cova A, Canese R, Jachetti E, Rossetti M, Huber V, Parmiani G, Generoso L, Santinami M, Borghi M, Fais S, Bellone M, Rivoltini L.

Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis.

PLoS One. 2012;7:e33418

Sonveaux P, Copetti T, De Saedeleer CJ, Végran F, Verrax J, Kennedy KM, Moon EJ, Dhup S, Danhier P, Frérart F, Gallez B, Ribeiro A, Michiels C, Dewhirst MW, Feron O.

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