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Press and newsletters

Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs -- an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research.

J Transl Med. 2013;11:282.

Harguindey S, Arranz JL, Polo Orozco JD, Rauch C, Fais S, Cardone RA, Reshkin SJ.

Vacuolar ATPase driven potassium transport in highly metastatic breast cancer cells.

Biochim Biophys Acta. 2013;1832:1734-43.

Salyer SA, Olberding JR, Distler AA, Lederer ED, Clark BJ, Delamere NA, Khundmiri SJ.

Disrupting proton dynamics and energy metabolism for cancer therapy

Nat Rev Cancer 2013; 13:611-623

Parks SK, Chiche J, Pouyssegur J

Catabolism of exogenous lactate reveals it as a legitimate metabolic substrate in breast cancer

Plos ONE 2013:8(9):e75154

Kennedy KM, Scarbrough PM, Ribeiro A, Richardson R, Yuan H, Sonveaux P, Landon CD, Chi JT, Pizzo S, Schroeder T, Dewhirst MW

Downregulation of MCT1 inhibits tumor growth, metastasis and enhances chemotherapeutic efficacy in osteosarcoma through regulation of the NF-κB pathway.

Cancer Lett. 2013 Sep 3. doi:pii: S0304-3835(13)00639-3. [Epub ahead of print]

Zhao Z, Wu MS, Zou C, Tang Q, Lu J, Liu D, Wu Y, Yin J, Xie X, Shen J, Kang T, Wang J.

Stromal glycolysis and MCT4 are hallmarks of DCIS progression to invasive breast cancer

Cell Cycle. 2013 Aug 27;12(18). [Epub ahead of print]

Lisanti MP, Sotgia F, Pestell RG, Howell A, Martinez-Outschoorn UE

Acidic extracellular microenvironment and cancer.

Cancer Cell Int. 2013 Sep 3;13:89.

Kato Y, Ozawa S, Miyamoto C, Maehata Y, Suzuki A, Maeda T, Baba Y.

Oncogenes induce the cancer-associated fibroblast phenotype: Metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discovery

Cell Cycle. 2013;12:2723-32

Lisanti MP, Martinez-Outschoorn UE, Sotgia F.

Proton pump inhibitor selectively suppresses proliferation and restores the chemosensitivity of gastric cancer cells by inhibiting STAT3 signaling pathway.

Int Immunopharmacol. 2013;17:585-592.

Huang S, Chen M, Ding X, Zhang X, Zou X.

NaV1.5 sodium channels allosterically regulate the NHE-1 exchanger and promote breast cancer cell invadopodial activity

J Cell Sci. 2013 Jul 31. In press

Brisson L, Driffort V, Benoist L, Poet M, Counillon L, Antelmi E, Rubino R, Besson P, Labbal F, Chevalier S, Reshkin SJ, Gore J, Roger S.

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