Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs -- an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research.
J Transl Med. 2013;11:282.
Press and newsletters
Vacuolar ATPase driven potassium transport in highly metastatic breast cancer cells.
Biochim Biophys Acta. 2013;1832:1734-43.
Disrupting proton dynamics and energy metabolism for cancer therapy
Nat Rev Cancer 2013; 13:611-623
Catabolism of exogenous lactate reveals it as a legitimate metabolic substrate in breast cancer
Plos ONE 2013:8(9):e75154
Downregulation of MCT1 inhibits tumor growth, metastasis and enhances chemotherapeutic efficacy in osteosarcoma through regulation of the NF-κB pathway.
Cancer Lett. 2013 Sep 3. doi:pii: S0304-3835(13)00639-3. [Epub ahead of print]
Stromal glycolysis and MCT4 are hallmarks of DCIS progression to invasive breast cancer
Cell Cycle. 2013 Aug 27;12(18). [Epub ahead of print]
Acidic extracellular microenvironment and cancer.
Cancer Cell Int. 2013 Sep 3;13:89.
Oncogenes induce the cancer-associated fibroblast phenotype: Metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discovery
Cell Cycle. 2013;12:2723-32
Proton pump inhibitor selectively suppresses proliferation and restores the chemosensitivity of gastric cancer cells by inhibiting STAT3 signaling pathway.
Int Immunopharmacol. 2013;17:585-592.
NaV1.5 sodium channels allosterically regulate the NHE-1 exchanger and promote breast cancer cell invadopodial activity
J Cell Sci. 2013 Jul 31. In press
